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Monkeypox Virus Evolution before 2022 Outbreak.
- Source :
-
Emerging infectious diseases [Emerg Infect Dis] 2023 Feb; Vol. 29 (2), pp. 451-453. - Publication Year :
- 2023
-
Abstract
- Phylogenetic analysis of monkeypox virus genomes showed statistically significant divergence and nascent subclades during the 2022 mpox outbreak. Frequency of G>A/C>T transitions has increased in recent years, probably resulting from apolipoprotein B mRNA editing enzyme catalytic polypeptide 3G (APOBEC3) deaminase editing. This microevolutionary pattern most likely reflects community spread of the virus and adaptation to humans.
Details
- Language :
- English
- ISSN :
- 1080-6059
- Volume :
- 29
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Emerging infectious diseases
- Publication Type :
- Editorial & Opinion
- Accession number :
- 36692511
- Full Text :
- https://doi.org/10.3201/eid2902.220962