Complex regional pain syndrome after mRNA-based COVID-19 vaccination.

Authors :: Horisawa S
Ando T
Kawamata T
Taira T
Source :: Clinical neurology and neurosurgery [Clin Neurol Neurosurg] 2023 Jan; Vol. 224, pp. 107578. Date of Electronic Publication: 2022 Dec 28.
Publication Year :: 2023
Abstract: We describe the case of a 17-year-old woman diagnosed with complex regional pain syndrome (CRPS) at a pain clinic after the second dose of the COVID-19 vaccine. She was referred to our department for surgical treatment of movement disorder seven months after the second inoculation. Baclofen (50 µg), administered intrathecally, improved the involuntary movements of her right hand. After administration of zolpidem (5 mg), involuntary movements of the right index finger almost disappeared. However, neither zolpidem nor intrathecal baclofen improved the limited range of motion of the first joint of the left-hand finger. Despite various reports on CRPS development after vaccination, only one case post COVID-19 vaccination has been reported. Therefore, healthcare providers should keep in mind that CRPS can appear after the COVID-19 vaccination.<br />Competing Interests: Declarations of interest None.<br /> (Copyright © 2022 Elsevier B.V. All rights reserved.)