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Does bariatric surgery change the risk of acute ischemic stroke in patients with a history of transient ischemic attack? A nationwide analysis.
- Source :
-
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery [Surg Obes Relat Dis] 2023 Jun; Vol. 19 (6), pp. 548-554. Date of Electronic Publication: 2022 Nov 23. - Publication Year :
- 2023
-
Abstract
- Background: Stroke is the second leading cause of death worldwide and fifth in the United States, and it represents the major cause of disability in older adults.<br />Objective: We aimed to determine the risk of acute ischemic stroke (AIS) in individuals with obesity with a history of transient ischemic attack (TIA) compared with patients with a history of bariatric surgery.<br />Setting: Academic hospital, United States.<br />Methods: Using the Nationwide Inpatient Sample (NIS) database from 2010 to 2015, we retrospectively identified patients with obesity and past medical history of TIA and divided them into 2 groups: a treatment group of patients who underwent bariatric surgery, and a control group of patients with obesity. We compared incidence of new AIS in both groups using a univariate analysis and multivariate regression model. Covariates included were lifestyle (smoking status, alcohol habits, cocaine use), family history of stroke, co-morbidities (diabetes, hypertension, hyperlipidemia, atrial fibrillation) and long-term medical treatment (antiplatelet/antithrombotic treatment).<br />Results: A total of 91,640 patients met inclusion criteria, of which treatment patients were 12.3% (n = 11,284) and control patients 87.6% (n = 80,356). The average age of the treatment group was 62.9 ± 17.08 years, and the average of the control was 59.6 ± 12.74 years. The rate of AIS in the treatment group was significantly lower compared with the control group (2.8% versus 4.2%, P < .0001). After adjusting for covariables, the risk difference of AIS was still significant between groups (odds ratio = 1.33, P < .0001), showing that patients in the treatment group were less likely to have AIS compared with the control group.<br />Conclusions: After analyzing nationwide information, we conclude bariatric surgery helps decrease risk of AIS in patients with a history of TIA. However, this comparison is limited by the nature of the database; further studies are needed to better understand these results.<br /> (Copyright © 2022 American Society for Metabolic and Bariatric Surgery. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Humans
United States epidemiology
Aged
Middle Aged
Aged, 80 and over
Retrospective Studies
Obesity complications
Risk Factors
Ischemic Attack, Transient epidemiology
Ischemic Attack, Transient etiology
Ischemic Stroke complications
Stroke epidemiology
Stroke etiology
Bariatric Surgery adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1878-7533
- Volume :
- 19
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 36581552
- Full Text :
- https://doi.org/10.1016/j.soard.2022.11.013