[Features of the course of lamellar macular holes with epiretinal proliferation].

The question of the course of lamellar macular holes (LMH) - favorable or progressive - remains controversial to this day. It is important to study the features of the course of this pathology in patients with epiretinal proliferation (EP).
Purpose: To establish the features of the course of lamellar macular holes with the presence of epiretinal proliferation.
Material and Methods: Clinical and instrumental monitoring was carried out in 48 patients with LMH divided into two groups: with the presence of EP ( n =27) and its absence ( n =21). The follow-up period lasted 15.9±2.3 months. The following parameters were assessed: changes in best corrected visual acuity (BCVA), mean retinal sensitivity (MRS) of the retina in 2- and 4-degree zones, subjective complaints; the main morphometric and morphostructural parameters of the retina were evaluated using optical coherence tomography (OCT).
Results: Patients with LMH and EP had lower initial BCVA, as well as, according to OCT, disruption of the ellipsoid zone and the presence of a foveal bump (37% and 22.2% of patients, respectively). During the follow-up, patients with EP showed an increase in subjective complaints, a statistically significant decrease in MRS in the 2-degree zone, and a decrease of the minimal retinal thickness.
Conclusion: LMH with EP are characterized by an unfavorable course, which is confirmed by a decrease in functional and anatomical parameters.