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Advancing drug discovery for glomerulopathies using stem-cell-derived kidney models.

Authors :
Barreto AD
Burt MA
Musah S
Source :
Trends in pharmacological sciences [Trends Pharmacol Sci] 2023 Apr; Vol. 44 (4), pp. 204-207. Date of Electronic Publication: 2022 Dec 22.
Publication Year :
2023

Abstract

Chronic kidney disease (CKD) is an epidemic that affects millions worldwide. The glomerulus, a specialized unit of the nephron, is highly susceptible to injury. Human induced pluripotent stem cells (iPSCs) have emerged as an attractive resource for modeling kidney disease and therapeutic discovery.<br />Competing Interests: Declaration of interests None declared by the authors.<br /> (Copyright © 2022 Elsevier Ltd. All rights reserved.)

Details

Language :
English
ISSN :
1873-3735
Volume :
44
Issue :
4
Database :
MEDLINE
Journal :
Trends in pharmacological sciences
Publication Type :
Academic Journal
Accession number :
36566132
Full Text :
https://doi.org/10.1016/j.tips.2022.12.001