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Sex-Associated Differences in Short-Term Outcomes in Patients with Deep Sternal Wound Infection after Open-Heart Surgery.

Sex-Associated Differences in Short-Term Outcomes in Patients with Deep Sternal Wound Infection after Open-Heart Surgery.

Authors :
Krasivskyi I
Ivanov B
Eghbalzadeh K
Fehlau F
Gerfer S
Großmann C
Elderia A
Sabashnikov A
Rahmanian PB
Mader N
Djordjevic I
Wahlers T
Source :
Journal of clinical medicine [J Clin Med] 2022 Dec 19; Vol. 11 (24). Date of Electronic Publication: 2022 Dec 19.
Publication Year :
2022

Abstract

Deep sternal wound infection (DSWI) is a feared complication after cardiac surgery. The impact of sex-related differences on wound infection prevalence is poorly understood. Our aim was to evaluate the effect of sex on short-term outcomes in patients with DSWI after open-heart surgery. The study was a retrospective cohort study. A total of 217 patients with DSWI were identified and retrospectively analyzed using our institutional database. Patients were divided into two groups: males ( n = 150) and females ( n = 67). This study also includes a propensity score based matching (PSM) analysis (male group ( n = 62) and female group ( n = 62)) to examine the unequal groups. Mean age ( p = 0.088) and mean body mass index (BMI) ( p = 0.905) did not significantly differ between both groups. Vacuum assisted closure (VAC) therapy was performed among most patients (82.3% (male group) vs. 83.9% (female group), p = 0.432). The most commonly isolated bacteria from the wounds were Staphylococcus epidermidis and Staphylococcus aureus in both groups. Acute renal failure was significantly higher ( p = 0.010) in the male group compared to the female group. However, dialysis rate did not significantly differ ( p = 0.491) between male and female groups. Further secondary outcomes showed no major differences between the groups. Likewise, in-hospital mortality rate did not differ significantly ( p = 0.680) between both groups. Based on our data, sex has no impact on deep wound infection prevalence after cardiac surgery.

Details

Language :
English
ISSN :
2077-0383
Volume :
11
Issue :
24
Database :
MEDLINE
Journal :
Journal of clinical medicine
Publication Type :
Academic Journal
Accession number :
36556125
Full Text :
https://doi.org/10.3390/jcm11247510