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Sex-Associated Differences in Short-Term Outcomes in Patients with Deep Sternal Wound Infection after Open-Heart Surgery.
Sex-Associated Differences in Short-Term Outcomes in Patients with Deep Sternal Wound Infection after Open-Heart Surgery.
- Source :
-
Journal of clinical medicine [J Clin Med] 2022 Dec 19; Vol. 11 (24). Date of Electronic Publication: 2022 Dec 19. - Publication Year :
- 2022
-
Abstract
- Deep sternal wound infection (DSWI) is a feared complication after cardiac surgery. The impact of sex-related differences on wound infection prevalence is poorly understood. Our aim was to evaluate the effect of sex on short-term outcomes in patients with DSWI after open-heart surgery. The study was a retrospective cohort study. A total of 217 patients with DSWI were identified and retrospectively analyzed using our institutional database. Patients were divided into two groups: males ( n = 150) and females ( n = 67). This study also includes a propensity score based matching (PSM) analysis (male group ( n = 62) and female group ( n = 62)) to examine the unequal groups. Mean age ( p = 0.088) and mean body mass index (BMI) ( p = 0.905) did not significantly differ between both groups. Vacuum assisted closure (VAC) therapy was performed among most patients (82.3% (male group) vs. 83.9% (female group), p = 0.432). The most commonly isolated bacteria from the wounds were Staphylococcus epidermidis and Staphylococcus aureus in both groups. Acute renal failure was significantly higher ( p = 0.010) in the male group compared to the female group. However, dialysis rate did not significantly differ ( p = 0.491) between male and female groups. Further secondary outcomes showed no major differences between the groups. Likewise, in-hospital mortality rate did not differ significantly ( p = 0.680) between both groups. Based on our data, sex has no impact on deep wound infection prevalence after cardiac surgery.
Details
- Language :
- English
- ISSN :
- 2077-0383
- Volume :
- 11
- Issue :
- 24
- Database :
- MEDLINE
- Journal :
- Journal of clinical medicine
- Publication Type :
- Academic Journal
- Accession number :
- 36556125
- Full Text :
- https://doi.org/10.3390/jcm11247510