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Abdominal Mass in a Phenotypic Female with 46,XY Differences in Sex Development.
- Source :
-
Urology [Urology] 2023 Mar; Vol. 173, pp. e13-e16. Date of Electronic Publication: 2022 Dec 19. - Publication Year :
- 2023
-
Abstract
- We present a case of a large intra-abdominal mass found to be localized pure seminoma within a retained gonad of a 53-year-old phenotypic female with 46,XY differences in sex development (DSD) and androgen insensitivity syndrome (AIS). Our management included extirpation of the mass with contralateral gonadectomy. Historically, patients with AIS would undergo gonadectomy to mitigate the lifetime risk of testicular germ cell tumor development; however, growing evidence suggests safety in retention and surveillance of these gonads into adulthood. This case highlights the importance of lifetime surveillance of patients with 46,XY DSD who elect to retain their gonads.<br /> (Copyright © 2022 Elsevier Inc. All rights reserved.)
- Subjects :
- Male
Humans
Female
Middle Aged
Gonads pathology
Sexual Development
Testicular Neoplasms surgery
Testicular Neoplasms pathology
Neoplasms, Germ Cell and Embryonal surgery
Neoplasms, Germ Cell and Embryonal pathology
Androgen-Insensitivity Syndrome surgery
Androgen-Insensitivity Syndrome pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1527-9995
- Volume :
- 173
- Database :
- MEDLINE
- Journal :
- Urology
- Publication Type :
- Report
- Accession number :
- 36549576
- Full Text :
- https://doi.org/10.1016/j.urology.2022.11.039