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Cancer risk among HIV-exposed uninfected children in the United States.
- Source :
-
AIDS (London, England) [AIDS] 2023 Mar 01; Vol. 37 (3), pp. 549-551. Date of Electronic Publication: 2022 Dec 22. - Publication Year :
- 2023
-
Abstract
- In utero exposure to didanosine was associated with increased risk of brain cancer in a French study. We used United States health department records to assess cancer risk among 13 617 children exposed to HIV in utero , who remained HIV-uninfected after birth (1990-2017). Risk of brain tumors was borderline elevated among these children (standardized incidence ratio 2.2, 95% confidence interval 0.8-4.8, P = 0.12, based on six cases). Risk was not significantly increased for leukemia or other cancers.<br /> (Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.)
- Subjects :
- Pregnancy
Female
Child
Humans
United States epidemiology
Infant
Prospective Studies
Anti-HIV Agents therapeutic use
Pregnancy Complications, Infectious drug therapy
HIV Infections complications
HIV Infections drug therapy
Prenatal Exposure Delayed Effects epidemiology
Prenatal Exposure Delayed Effects chemically induced
Neoplasms epidemiology
Neoplasms drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1473-5571
- Volume :
- 37
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- AIDS (London, England)
- Publication Type :
- Academic Journal
- Accession number :
- 36544264
- Full Text :
- https://doi.org/10.1097/QAD.0000000000003458