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[Leber hereditary optic neuropathy: update on genetics and pathomechanisms].

Authors :
Smimov VM
Source :
Journal francais d'ophtalmologie [J Fr Ophtalmol] 2022 Nov; Vol. 45 (8S1), pp. S17-S23.
Publication Year :
2022

Abstract

Leber Hereditary Optic Neuropathy is still a dramatic disease of optic nerve. Origins and mechanisms are extensively studied in the last decades, in link with emergent therapeutic approaches. This article is an update on genetics and pathophysiology of LHON and leber-like inherited optic neuropathies.<br /> (Copyright © 2022 Publié par Elsevier Masson SAS. All rights reserved.)

Subjects

Subjects :
Humans
DNA, Mitochondrial
Optic Nerve
Mutation
Optic Atrophy, Hereditary, Leber diagnosis
Optic Atrophy, Hereditary, Leber genetics
Optic Atrophy, Hereditary, Leber therapy
Optic Nerve Diseases etiology
Optic Nerve Diseases genetics

Details

Language :
French
ISSN :
1773-0597
Volume :
45
Issue :
8S1
Database :
MEDLINE
Journal :
Journal francais d'ophtalmologie
Publication Type :
Academic Journal
Accession number :
36529473
Full Text :
https://doi.org/10.1016/S0181-5512(22)00446-6
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