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Associations of Physical Inactivity and COVID-19 Outcomes Among Subgroups.
- Source :
-
American journal of preventive medicine [Am J Prev Med] 2023 Apr; Vol. 64 (4), pp. 492-502. Date of Electronic Publication: 2022 Dec 15. - Publication Year :
- 2023
-
Abstract
- Introduction: Physical activity before COVID-19 infection is associated with less severe outcomes. The study determined whether a dose‒response association was observed and whether the associations were consistent across demographic subgroups and chronic conditions.<br />Methods: A retrospective cohort study of Kaiser Permanente Southern California adult patients who had a positive COVID-19 diagnosis between January 1, 2020 and May 31, 2021 was created. The exposure was the median of at least 3 physical activity self-reports before diagnosis. Patients were categorized as follows: always inactive, all assessments at 10 minutes/week or less; mostly inactive, median of 0-60 minutes per week; some activity, median of 60-150 minutes per week; consistently active, median>150 minutes per week; and always active, all assessments>150 minutes per week. Outcomes were hospitalization, deterioration event, or death 90 days after a COVID-19 diagnosis. Data were analyzed in 2022.<br />Results: Of 194,191 adults with COVID-19 infection, 6.3% were hospitalized, 3.1% experienced a deterioration event, and 2.8% died within 90 days. Dose‒response effects were strong; for example, patients in the some activity category had higher odds of hospitalization (OR=1.43; 95% CI=1.26, 1.63), deterioration (OR=1.83; 95% CI=1.49, 2.25), and death (OR=1.92; 95% CI=1.48, 2.49) than those in the always active category. Results were generally consistent across sex, race and ethnicity, age, and BMI categories and for patients with cardiovascular disease or hypertension.<br />Conclusions: There were protective associations of physical activity for adverse COVID-19 outcomes across demographic and clinical characteristics. Public health leaders should add physical activity to pandemic control strategies.<br /> (Copyright © 2022 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Humans
Male
Female
Middle Aged
Aged
Hospitalization statistics & numerical data
California
Retrospective Studies
Disease Progression
Sedentary Behavior
Time Factors
Racial Groups statistics & numerical data
Ethnicity statistics & numerical data
Body Mass Index
Cardiovascular Diseases epidemiology
Hypertension epidemiology
Exercise physiology
COVID-19 classification
COVID-19 diagnosis
COVID-19 mortality
COVID-19 physiopathology
Subjects
Details
- Language :
- English
- ISSN :
- 1873-2607
- Volume :
- 64
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- American journal of preventive medicine
- Publication Type :
- Academic Journal
- Accession number :
- 36528452
- Full Text :
- https://doi.org/10.1016/j.amepre.2022.10.007