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Real-world evidence on atopic dermatitis: Baseline characteristics and predictors of treatment choice in the TARGET cohort.

Authors :
Abuabara K
Eichenfield LF
Bissonnette R
Silverberg JI
Bagel J
Guttman-Yassky E
Thaci D
Simpson EL
Harris JE
Krueger J
Myers DE
Gamelli A
Milutinovic M
Parneix A
Crawford JM
Hildebrand JS
Munoz B
Paller AS
Source :
Journal of the American Academy of Dermatology [J Am Acad Dermatol] 2023 Aug; Vol. 89 (2), pp. 345-347. Date of Electronic Publication: 2022 Dec 13.
Publication Year :
2023

Abstract

Competing Interests: Conflicts of interest Dr Abuabara is a TARGET consulting member and received grants from Cosmetique Internacional SNC and Pfizer (paid to Institution). Dr Eichenfield is a consultant, speaker, and advisory board member for Almirall, Dermavant, Dermira, DS-Biopharma, Forte, Galderma, Incyte, LEO, Lilly, L’Oreal, Matrisys, Otsuka, Novartis, Ortho Dermatologics/Valeant, Pfizer/Anacor, Regeneron, Sanofi-Genzyme; and an investigator for Abvie, LEO, Regeneron, Sanofi-Genzyme. DSM: Asana, Ichnos/Glenmark. Dr Bissonnette is an advisory board member, consultant, speaker, and/or investigator for and receives honoraria and/or grant from AbbVie, Arcutis, Arena Pharma, Aristea, Asana BioSciences, Bellus Health, Bluefin Biomedicine, Boehringer-Ingelheim, CARA, Dermavant, Eli Lilly, EMD Serono, Evidera, Galderma, GSK, Inmagene Bio, Incyte, Kiniksa, Kyowa Kirin, LEO Pharma, Novan, Pfizer, Ralexar, RAPT, Regeneron, Respivant, Sanofi-Genzyme, Sienna, Target RWE and Vyne Therapeutics. Dr Bissonnette is also an employee and shareholder of Innovaderm Research. Dr Silverberg received honoraria as a consultant and/or advisory board member for AbbVie, Afyx, Aobiome, Arena, Asana, BioMX, Bluefin, Bodewell, Boehringer-Ingelheim, Celgene, Dermavant, Dermira, Eli Lilly, Galderma, GlaxoSmithKline, Incyte, Kiniksa, Leo Pharma, Luna, Menlo, Novartis, Pfizer, RAPT, Regeneron, Sanofi-Genzyme; speaker for AbbVie, Eli Lilly, Leo Pharma, Pfizer, Regeneron, Sanofi-Genzyme; Institution received grants from Galderma, Pfizer. Dr Bagel received research funds payable to the Psoriasis Treatment Center of New Jersey from AbbVie, Amgen, Arcutis Biotherapeutics, Boehringer-Ingelheim, Brickell Biotech, Inc., Bristol-Myers Squibb, Celgene Corporation, Corrona LLC, Dermavant Sciences, LTD, Dermira, Eli Lilly and Company, Janssen Biotech, Kadmon Corporation, Leo Pharma, Menlo Therapeutics, Mindera, Novartis, Pfizer, Regeneron Pharmaceuticals, Sanofi, Sun Pharma, Target Pharma, Taro Pharmaceutical Industries Ltd, UCB, and Valeant Pharmaceuticals; consultant fees from AbbVie, Amgen, Arcutis Biotherapeutics, Bristol-Myers Squibb, Celgene Corporation, Dermavant Sciences, Eli Lilly and Company, Janssen Biotech, Mindera, Novartis, Sun Pharmaceutical Industries Ltd, UCB, and Valeant Pharmaceuticals; and fees for speaking from AbbVie, Celgene Corporation, Eli Lilly, Janssen Biotech, and Novartis. Dr Guttman-Yassky is an advisory board member for Aditum Bio, DBV, Dermira, Ventyx, Novartis; consultant for Celgene, DBV, Dermavant, Dermira, DS-Biopharma, Union Therapeutics, Ventyx, Novartis, Boston Pharmaceuticals, Principia, Vanda Pharmaceuticals; investigator for Dermira, and received grants from Celgene, DBV, DS-Biopharma. Dr Thaci is a lecturer and/or consultant for AbbVie, Almirall, Amgen, Asana Biosciences, Biogen Idec, BIOCAD, Boehringer-Ingelheim, Bristol-Myers Squibb, Celgene, DS-Biopharma, GlaxoSmithKline, Janssen-Cilag, Kyowa Kirin, Leo Pharma, Eli Lilly, Novartis, Regeneron, Sandoz, Sanofi-Aventis and UCB, and received grants from AbbVie and Novartis (paid to Institution). Dr Simpson received personal fees from AbbVie, Amgen, Arena Pharmaceuticals, Aslan Pharma, Boston Consulting Group, Collective Acumen, LLC (CA), Dermira, Eli Lilly, Evidera, ExcerptaMedica, Forte Bio RX, Galderma, GlaxoSmithKline, Incyte, Janssen, Kyowa Kirin Pharmaceutical Development, Leo Pharm, Medscape LLC, Pfizer, Physicians World LLC, Regeneron, Sanofi-Genzyme, Trevi therapeutics, WebMD; received reports grants (or Principal investigator role) from AbbVie, Amgen, Arcutis, Corevita, Dermira, Eli Lilly, Incyte, Kyowa Hakko Kirin, Leo Pharmaceuticals, Merck, Novartis, Pfizer, Regeneron, Sanofi, TARGET-DERM, Tioga, and Vanda. These potential conflicts of interest have been reviewed and managed by OHSU. Dr Harris is a consultant for Pfizer, Genzyme/Sanofi, Incyte, Rheos Medicines, Sun Pharmaceuticals, LEO Pharma, Villaris Therapeutics, Inc., Dermavant, TeVido BioDevices, Temprian Therapeutics, AbbVie, Inc, Janssen, Almirall, Methuselah Health, Pandion, AnaptysBio, Avita, NIRA Biosciences, Aclaris Therapeutics, EMD Serono, The Expert Institute, BiologicsMD, Boston Pharma, Sonoma Biotherapeutics, Twi Biotech, Admirx, Frazier Management, 3rd Rock Ventures, Cogen Therapeutics, Granular Therapeutics, Inc., Platelet Biogenesis, Inc., Aldena; investigator for Pfizer, Genzyme/Sanofi, Incyte, Rheos Medicines, Sun Pharmaceuticals, LEO Pharma, Villaris Therapeutics, Inc., Dermavant, TeVido BioDevices, Aclaris Therapeutics, Stiefel/GSK, Celgene, Dermira, EMD Serono; a shareholder of TeVido BioDevices, Rheos, Villaris Therapeutics, Inc., NIRA Biosciences, Aldena; and founder of Villaris Therapeutics, Inc., NIRA Biosciences, Aldena. Dr Krueger received personal fees from Novartis, Pfizer, Amgen, Lilly, Boehringer, BMS, Biogenldec, Janssen, AbbVie, Leo Pharma, ESCALIER, Valeant, Allergan, Aurigene, Sienna, UCB, Allergan, Asana, Celgene, Nimbus, Menlo, Aristea, Sanofi, Sun Pharma, Almirall, Arena, Ventyx, Aclaris, Galapagos; and grants paid to Institution from Novartis, Pfizer, Amgen, Lilly, Boehringer, Innovaderm, BMS, Janssen, AbbVie, Parexel, Leo Pharma, Vitae, Akros, Regeneron, Allergan, Novan, Biogen MA, Sienna, UCB, Celgene, Botanix, Incyte, Avillion, and Exicure. Dr Myers is an employee and shareholder of Pfizer Inc. Dr Gamelli is a full-time employee of AbbVie Inc. and shareholder of AbbVie stocks or stock options. Dr Milutinovic is an employee and stockholder of Novartis Pharma AG. Dr Parneix is an employee and shareholder of Novartis. Drs Crawford and Munoz are employees of Target RWE. Dr Paller is an investigator for AbbVie, AnaptysBio, Eli Lilly, Incyte, Janssen, KrystalBio, Regeneron, UCB; Consultant with honorarium–AbbVie, Abeona, Alcimed, Almirall, Amagma, Anaptysbio, Arena, Azitra, BiomX, Boehringer Ingeheim, Castle Biosciences, Catawba, Dermira, Eli Lilly, Exicure, Forte, Kamari, Leo, Lifemax, NAOS, Novartis, Pfizer, Phoenix, Pierre Fabre, Regeneron, Sanofi/Genzyme, Seanergy, Trifecta, UCB; and a member of the Data Safety Monitoring Board of AbbVie, Bausch, Galderma, Novan.

Details

Language :
English
ISSN :
1097-6787
Volume :
89
Issue :
2
Database :
MEDLINE
Journal :
Journal of the American Academy of Dermatology
Publication Type :
Editorial & Opinion
Accession number :
36521798
Full Text :
https://doi.org/10.1016/j.jaad.2022.08.065