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The Impact of Covid-19 Pandemic on Genitourinary Cancers Stage and Grade.

Authors :: Taheri D
Jahanshahi F
Khajavi A
Kafi F
Pouramini A
Farsani RM
Alizadeh Y
Akbarzadeh M
Reis LO
Khatami F
Aghamir SMK
Source :: Clinical genitourinary cancer [Clin Genitourin Cancer] 2023 Feb; Vol. 21 (1), pp. 84-90. Date of Electronic Publication: 2022 Nov 24.
Publication Year :: 2023
Abstract: Introduction: Our study aims to evaluate the impact of the COVID-19 pandemic on the number of uro-oncological surgeries (cystectomy, nephrectomy, prostatectomy, orchiectomy, and transurethral resection of bladder tumor (TURBT)) and pathological staging and grading.<br />Materials and Methods: The present study is a retrospective study on patients with genitourinary cancers treated from 2018 to 2021 in a referral tertiary center. The data were obtained from the hospital records with lengths of 22 and 23 months, labeled hereafter as non-COVID and COVID pandemic, respectively (2018/3/21-2020/1/20 and 2020/1/21-2021/12/21). The total number of registered patients, gender, age, stage, and grade were compared in the targeted periods. Moreover, all the pathologic slides were reviewed by an expert uropathologist before enrolling in the study. The continuous and discrete variables are reported as mean (standard deviation (SD)) and number (percent) and the χ <superscript>2</superscript> test for the comparison of the discrete variables' distribution.<br />Results: In this study total number of 2077 patients were enrolled. The number of procedures performed decreased during the Covid pandemic. The tumors' distribution stage and grade and patients' baseline characteristics were not significantly different in non-COVID and COVID pandemic periods for Radical Nephrectomy, Radical Cystectomy, Radical Prostatectomy, and orchiectomy. For TURBT only, the tumor stage was significantly different (P-value<.001) from the higher stages in the COVID pandemic period.<br />Conclusion: Among urinary tract cancers, staging of bladder cancer and TURBT are mainly impacted by the COVID-19 pandemic with higher stages compared to the non-COVID period. We evaluate the impact of the COVID-19 pandemic on the number of uro-oncological surgeries based on pathological staging and grading. Total number of 2077 patients were enrolled. Among urinary tract cancers, staging of bladder cancer and TURBT are mainly impacted by the COVID-19 pandemic with higher stages compared to the non-COVID period.<br /> (Copyright © 2022 Elsevier Inc. All rights reserved.)