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Rewiring the logic board of IFN signaling.

Authors :
MacMicking JD
Source :
Science signaling [Sci Signal] 2022 Dec 13; Vol. 15 (764), pp. eadf0778. Date of Electronic Publication: 2022 Dec 13.
Publication Year :
2022

Abstract

Interferons (IFNs) activate cell-autonomous immunity to combat infection and control inflammation. In this issue of Science Signaling , Boccuni et al. reveal how macrophages incorporate stress signals through the p38 MAPK pathway to enhance IFN-induced responses against intracellular pathogens.

Details

Language :
English
ISSN :
1937-9145
Volume :
15
Issue :
764
Database :
MEDLINE
Journal :
Science signaling
Publication Type :
Academic Journal
Accession number :
36512642
Full Text :
https://doi.org/10.1126/scisignal.adf0778