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Quantitative assessment of depolarization by the retinal pigment epithelium in healthy and glaucoma subjects measured over a large field of view.

Authors :
Motschi AR
Schwarzhans F
Desissaire S
Steiner S
Bogunović H
Roberts PK
Vass C
Hitzenberger CK
Pircher M
Source :
PloS one [PLoS One] 2022 Dec 13; Vol. 17 (12), pp. e0278679. Date of Electronic Publication: 2022 Dec 13 (Print Publication: 2022).
Publication Year :
2022

Abstract

We present measurements of depolarization introduced by the retinal pigment epithelium (RPE) over a 45° field of view using polarization sensitive optical coherence tomography. A detailed spatial distribution analysis of depolarization caused by the RPE is presented in a total of 153 subjects including both healthy and diseased eyes. Age and sex related differences in the depolarizing character of the RPE are investigated.<br />Competing Interests: The authors have declared that no competing interests exist.<br /> (Copyright: © 2022 Motschi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

Details

Language :
English
ISSN :
1932-6203
Volume :
17
Issue :
12
Database :
MEDLINE
Journal :
PloS one
Publication Type :
Academic Journal
Accession number :
36512582
Full Text :
https://doi.org/10.1371/journal.pone.0278679