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Persistent isolated impairment of gas transfer following COVID-19 pneumonitis relates to perfusion defects on dual-energy computed tomography.

Authors :
Price LC
Garfield B
Bloom C
Jeyin N
Nissan D
Hull JH
Patel B
Jenkins G
Padley S
Man W
Singh S
Ridge CA
Source :
ERJ open research [ERJ Open Res] 2022 Nov 28; Vol. 8 (4). Date of Electronic Publication: 2022 Nov 28 (Print Publication: 2022).
Publication Year :
2022

Abstract

A novel iodine perfusion score correlates with breathlessness and D <subscript>LCO</subscript> in patients post-#COVID19 without obvious interstitial disease on CT, suggesting that lung perfusion assessment may be useful in patients without another cause of dyspnoea https://bit.ly/3U6E2f5.<br />Competing Interests: Conflicts of interest: L.C. Price has grants from Janssen and GSK, not relevant to the work and has received consulting fees from and Participated on a Data Safety Monitoring Board or Advisory Board for Janssen, outside the submitted work. C. Bloom has received grants from NIHR Advanced Fellowship, Imperial College NIHR BRC project funding and Imperial College Covid-19 project fund, outside the submitted work. C. Bloom has a leadership or fiduciary role at the Policy Forum Primary Care Respiratory Society. B. Patel has received grants from European Commission Horizon 2020, Mermaid A/C investigator led grant, Royal Brompton & Harefield Charity grant and Imperial College London Covid Response Grant; has received consulting fees from Apogenix AG, InspiraTech, StromaBio, Nitrase Therapeutics and Gilead Sciences Ltd; and has participated in a Data Safety Monitoring Board or Advisory Board for Faraday Pharmaceuticals, all outside the submitted work. G. Jenkins has grants from AstraZeneca, Biogen, Galecto, GSK, RedX, Pliant, Genetech, Bristol Myers Squibb, Daewong, Veracyt, Chiesi and Boehringer Ingelheim, not related to the work. G. Jenkins has received consulting fees from Bristol Myers Squibb, Daewoong, Veracyte, Resolution Therapeutics, RedX, Pliant and Chiesi; payment or honoraria for lectures, presentations, speakers' bureaus, manuscript writing or educational events from Chiesi, Roche, PatientMPower, AstraZeneca, GSK and Boehringer Ingelheim; participation on a Data Safety Monitoring Board or Advisory Board for Boehringer Ingelheim, Galapagos, Vicore and Roche; and has a leadership or fiduciary role at NuMedii and Action for Pulmonary Fibrosis (trustee), all outside the submitted work. W. Man has received grants from National Institute for Health Research, British Lung Foundation and NHS Accelerated Access Collaborative; payment or honoraria for lectures, presentations, speakers' bureaus, manuscript writing or educational events from European Conference and Incentive Services DMC; has participated on a Data Safety Monitoring Board or Advisory Board for Jazz Pharmaceuticals; and funds for blood analysis from GSK, all outside the submitted work. S. Singh has grants from Anbu and Fischer and Paykel, not related to the work. J.H. Hull and W. Man are associate editors of this journal. B. Garfield, N. Jeyin, D. Nissan, S. Padley and C.A. Ridge have no conflicts to disclose.<br /> (Copyright ©The authors 2022.)

Details

Language :
English
ISSN :
2312-0541
Volume :
8
Issue :
4
Database :
MEDLINE
Journal :
ERJ open research
Publication Type :
Academic Journal
Accession number :
36447736
Full Text :
https://doi.org/10.1183/23120541.00224-2022