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Chromatographic Methods for the Determination of Rifampicin, Isoniazid, Pyrazinamide, Ethambutol, and Main Metabolites in Biological Samples: A Review.
- Source :
-
Critical reviews in analytical chemistry [Crit Rev Anal Chem] 2024; Vol. 54 (7), pp. 1971-1986. Date of Electronic Publication: 2022 Nov 29. - Publication Year :
- 2024
-
Abstract
- Bioanalytical methods are used to quantify drugs and their metabolites in biological samples in order to determine bioequivalence, perform pharmacokinetic and bioavailability studies, and complete therapeutic drug monitoring. The objective of this review paper is to describe bioanalytical methods based on Liquid Chromatography that are used to quantify antitubercular drugs and their metabolites in different biological samples, utilizing scientific literature from 1992 to 2021.
- Subjects :
- Humans
Chromatography, Liquid methods
Antitubercular Agents analysis
Antitubercular Agents pharmacokinetics
Antitubercular Agents blood
Antitubercular Agents metabolism
Isoniazid analysis
Isoniazid pharmacokinetics
Isoniazid metabolism
Isoniazid blood
Pyrazinamide analysis
Pyrazinamide pharmacokinetics
Pyrazinamide metabolism
Pyrazinamide blood
Ethambutol analysis
Ethambutol blood
Ethambutol pharmacokinetics
Ethambutol metabolism
Rifampin analysis
Rifampin pharmacokinetics
Rifampin metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1547-6510
- Volume :
- 54
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Critical reviews in analytical chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 36444713
- Full Text :
- https://doi.org/10.1080/10408347.2022.2150071