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Uretero-enteric Strictures After Robot Assisted Radical Cystectomy: Prevalence and Management Over Two Decades.
- Source :
-
Clinical genitourinary cancer [Clin Genitourin Cancer] 2023 Apr; Vol. 21 (2), pp. e19-e26. Date of Electronic Publication: 2022 Oct 12. - Publication Year :
- 2023
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Abstract
- Introduction: To evaluate the prevalence, predictors, management, and trends for ureteroenteric strictures (UES) after robot-assisted radical cystectomy (RARC).<br />Methods: Retrospective review of our RARC database was performed (2005-2022). UES was described in terms of timing, laterality, and management. Kaplan-Meier curves were used to depict time to UES. Local regression was used to assess trend of UES over time and multivariable regression to identify variables associated with UES.<br />Results: UES occurred in 109 patients (15%). UES occurred in 13%, 17%, and 19% at 1, 3, and 5 years after RARC, respectively. Incidence of UES decreased in 2017, coinciding with stentless uretero-enteric anastomosis. UES occurred on the right in 33%, on the left in 46%, and bilaterally in 21%. All patients were initially managed by nephrostomy/stent. Surgical revision was required in 45% of patients, of which 13% developed recurrent UES after revision. On MVA, UES formation was associated with ureteral stents (OR 2.27, 95%CI 1.01-5.10, P = .05) and receipt of neoadjuvant chemotherapy (OR 2.01, 95%CI 1.24-3.25, P = .005).<br />Conclusion: UES occurred in 15% of patients after RARC, with 45% of patients requiring surgical reimplantation. Ureteral stents and the receipt of neoadjuvant chemotherapy were associated with UES formation.<br />Competing Interests: Disclosure The authors have stated that they have no conflicts of interest.<br /> (Published by Elsevier Inc.)
- Subjects :
- Humans
Cystectomy adverse effects
Constriction, Pathologic epidemiology
Constriction, Pathologic etiology
Constriction, Pathologic surgery
Prevalence
Postoperative Complications epidemiology
Postoperative Complications etiology
Postoperative Complications therapy
Retrospective Studies
Treatment Outcome
Urinary Diversion adverse effects
Robotics
Urinary Bladder Neoplasms surgery
Urinary Bladder Neoplasms complications
Robotic Surgical Procedures adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1938-0682
- Volume :
- 21
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Clinical genitourinary cancer
- Publication Type :
- Academic Journal
- Accession number :
- 36372690
- Full Text :
- https://doi.org/10.1016/j.clgc.2022.10.006