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Relative prevalence and outcome of fetal posterior fossa abnormality.
- Source :
-
Journal of paediatrics and child health [J Paediatr Child Health] 2023 Jan; Vol. 59 (1), pp. 107-115. Date of Electronic Publication: 2022 Nov 01. - Publication Year :
- 2023
-
Abstract
- Aim: To find out the relative incidence and outcome of posterior fossa abnormality (PFA) in terms of survival at birth until 2 years of age.<br />Methods: We conducted a prospective study; all fetuses diagnosed with posterior fossa abnormality were followed-up. The outcome was observed with respect to survival, the presence of associated anomalies, the existence of developmental delay after a telephonic interview.<br />Results: Out of 2703 children with congenital anomalies, 921 (34.1%) had a central nervous system defect; 76 cases of PFA were fully followed. Dandy-Walker malformation (DWM) was present in 50% (38/76), mega cisterna magna 18.4% (14/76), Blake pouch cyst 13.2% (10/76), vermian hypoplasia (VH) 13.2% (10/76) and arachnoid cyst 5.2% (4/76). The diagnosis was possible before 20 weeks in only 12 (15.8%) cases. The mean gestational age at delivery was 34.7 ± 6.7 weeks. Associated anomalies were seen in 35/76 (46.1%) cases. A total of 35/76 (46.1%) survived after 2 years; there was developmental delay in 9.2% of cases.<br />Conclusion: There is a large variation in the outcome of PFA depending upon the type of anomaly. Associated anomalies are common in VH and DWM, making their prognosis worse.<br /> (© 2022 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).)
Details
- Language :
- English
- ISSN :
- 1440-1754
- Volume :
- 59
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of paediatrics and child health
- Publication Type :
- Academic Journal
- Accession number :
- 36318816
- Full Text :
- https://doi.org/10.1111/jpc.16254