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Two new monoterpene esters from Illigera paviflora Dunn roots.

Authors :
Jiang MY
Pu XY
Li WT
Liu J
Zeng XL
Li HR
Bai XS
Hu L
Huang XZ
Source :
Natural product research [Nat Prod Res] 2024 Apr; Vol. 38 (7), pp. 1230-1237. Date of Electronic Publication: 2022 Oct 26.
Publication Year :
2024

Abstract

Two new monoterpene esters, illigerates H and I ( 1 and 2 ), and six known compounds actinodaphine ( 3 ), bulbocupnine ( 4 ), stephanine ( 5 ), hypserpanine B ( 6 ), betulinic acid ( 7 ) and gallic acid ( 8 ) were obtained from the root of Illigera paviflora Dunn. Their structures were elucidated by spectroscopic analysis. Anti-inflammatory and α-glucosidase inhibitory activity of some isolated compounds were assessed. Two monoterpenes 1 and 2 exhibited weak in vitro anti-inflammatory activity (IC <subscript>50</subscript> 64.5 ± 5.3 and 79.2 ± 7.5 μM) while compounds 3-6 showed inhibition of α-glucosidase with IC <subscript>50</subscript> values ranged from 87.17 to 118.74 μM.

Details

Language :
English
ISSN :
1478-6427
Volume :
38
Issue :
7
Database :
MEDLINE
Journal :
Natural product research
Publication Type :
Academic Journal
Accession number :
36287603
Full Text :
https://doi.org/10.1080/14786419.2022.2137802