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Dinuclear osmium complexes as mitochondrion-targeting antitumor photothermal agents in vivo .
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2022 Nov 15; Vol. 58 (91), pp. 12676-12679. Date of Electronic Publication: 2022 Nov 15. - Publication Year :
- 2022
-
Abstract
- Four dinuclear osmium complexes have been constructed for antitumor phototherapy. The most potent Os4 has extremely high photothermal conversion capability under irradiation of an 808 nm low-power laser, targets mitochondria in human melanoma cells without nucleus affinity, and acts as an antitumor photothermal therapy agent in vitro and in vivo .
Details
- Language :
- English
- ISSN :
- 1364-548X
- Volume :
- 58
- Issue :
- 91
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 36286391
- Full Text :
- https://doi.org/10.1039/d2cc05230j