Back to Search
Start Over
Comparison of analgesic consumption of hemophilic and non-hemophilic patients in knee arthroplasty.
- Source :
-
Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES [Ulus Travma Acil Cerrahi Derg] 2022 Nov; Vol. 28 (11), pp. 1616-1621. - Publication Year :
- 2022
-
Abstract
- Background: Hemophilia is a rare hereditary bleeding disorder that develops as a result of factor VIII or IX deficiency. Long-term complications of hemophilia such as arthropathy, synovitis, and arthritis can lead to the development of recurrent chronic pain. Pain is therefore a critical aspect of hemophilia. The gold standard treatment for end-stage hemophilic knee arthropathy is total knee arthroplasty (TKA). The hypothesis of this study was that after knee replacement surgeries that cause severe post-operative pain, hemophilia patients with chronic analgesic consumption may experience higher levels of pain than non-hemophilic patients, and use more opioid and non-opioid drugs.<br />Methods: This retrospective study included 82 patients who were hemophilic and non-hemophilic TKA patients operated under general anesthesia. Seventy-three patients were evaluated and divided into two groups according to the diagnosis of hemophilia: 36 patients were investigated in the hemophilic group and 37 patients in the non-hemophilic group.<br />Results: Post-operative tramadol consumption (p=0.002) and pethidine consumption (p=0.003) were significantly higher in the group hemophilia. The length of stay in the hospital was also significantly longer in the hemophilic group (p=0.0001).<br />Conclusion: In the light of these informations, we think that acute post-operative pain management of hemophilia patients should be planned as personalized, multimodal preventive, and pre-emptive analgesia.
- Subjects :
- Humans
Factor VIII therapeutic use
Retrospective Studies
Pain etiology
Analgesics therapeutic use
Meperidine therapeutic use
Arthroplasty, Replacement, Knee adverse effects
Arthroplasty, Replacement, Knee methods
Hemophilia A complications
Hemophilia A drug therapy
Hemophilia A surgery
Tramadol therapeutic use
Joint Diseases complications
Joint Diseases surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1307-7945
- Volume :
- 28
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
- Publication Type :
- Academic Journal
- Accession number :
- 36282160
- Full Text :
- https://doi.org/10.14744/tjtes.2021.47482