Ullmann homocoupling of arenediazonium salts in a deep eutectic solvent. Synthetic and mechanistic aspects.

Authors :: Ghigo G
Bonomo M
Antenucci A
Damin A
Dughera S
Source :: RSC advances [RSC Adv] 2022 Sep 20; Vol. 12 (41), pp. 26640-26647. Date of Electronic Publication: 2022 Sep 20 (Print Publication: 2022).
Publication Year :: 2022
Abstract: A deep eutectic solvent (DES) based on glycerol and KF is successfully exploited as a solvent medium in Ullmann homocoupling of arenediazonium salts. The reactions were carried out in mild conditions and target products were obtained in fairly good yields. A computational study is presented aiming to understand the reaction mechanism and Raman spectroscopy is employed as an experimental tool to support it.<br />Competing Interests: There are no conflicts to declare.<br /> (This journal is © The Royal Society of Chemistry.)

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