Back to Search Start Over

5-Fluoro-1,2,3-triazole motif in peptides and its electronic properties.

Authors :
Laxio Arenas J
Retailleau P
Gillet JM
Ghermani NE
Ongeri S
Crousse B
Source :
Organic & biomolecular chemistry [Org Biomol Chem] 2022 Nov 09; Vol. 20 (43), pp. 8410-8414. Date of Electronic Publication: 2022 Nov 09.
Publication Year :
2022

Abstract

The 5-fluoro triazole amino acid scaffold prepared by halogen exchange has been incorporated into peptides. From the X-ray diffraction of the 5-fluoro triazole motif, the main observation was an important localization on one side of the negative potential surface. The fluorine atom reveals a cylindrical shape in its deformation electron density.

Details

Language :
English
ISSN :
1477-0539
Volume :
20
Issue :
43
Database :
MEDLINE
Journal :
Organic & biomolecular chemistry
Publication Type :
Academic Journal
Accession number :
36263672
Full Text :
https://doi.org/10.1039/d2ob01716d