Back to Search Start Over

A Novel Imaging Technique for The On-site Assessment of Renal Biopsy Specimens.

Authors :
Takata T
Isomoto H
Iyama T
Yamada K
Source :
Bio-protocol [Bio Protoc] 2022 Sep 20; Vol. 12 (18). Date of Electronic Publication: 2022 Sep 20 (Print Publication: 2022).
Publication Year :
2022

Abstract

When performing renal biopsy, it is necessary to identify the cortex, where glomeruli are exclusively distributed, to ensure the quality of the specimen for histological diagnosis. However, conventional methods using a stereomicroscope or magnifying lens often fail to clarify the quality of the specimen. We have established a fluorescent-based imaging technique for the on-site assessment of renal biopsy specimens. The fluorescent images can be easily obtained by adding an optical filter to the microscope and with a short incubation of an activatable fluorescent probe. This novel imaging technique can be applied to renal biopsy specimens for distinguishing the renal cortex.<br />Competing Interests: Competing interests The authors declare that they have no financial or non-financial conflicts of interest.<br /> (Copyright © 2022 The Authors; exclusive licensee Bio-protocol LLC.)

Details

Language :
English
ISSN :
2331-8325
Volume :
12
Issue :
18
Database :
MEDLINE
Journal :
Bio-protocol
Publication Type :
Academic Journal
Accession number :
36248605
Full Text :
https://doi.org/10.21769/BioProtoc.4517