Pain in neuromyelitis optic spectrum disorder.

Authors :: Xue H
Yang W
Zhao Y
Wang L
Wang G
Zhang M
Zhang H
Source :: Multiple sclerosis and related disorders [Mult Scler Relat Disord] 2022 Dec; Vol. 68, pp. 104192. Date of Electronic Publication: 2022 Sep 23.
Publication Year :: 2022
Abstract: Background: Pain is a common symptom of neuromyelitis optica spectrum disorder (NMOSD), but there are relatively few studies on NMOSD pain. Methods: We retrospectively reviewed the medical records of 145 patients with NMOSD admitted to our hospital between July 2016 and June 2019. Results: The clinical characteristics of pain and factors related to NMOSD were analyzed, revealing that the incidence of pain in NMOSD is high and can be used for disease localization. Conclusion: Different types of pain occur at different stages of the disease, and serum aquaporin-4 antibody (AQP4-ab) positivity is an independent risk factor for NMOSD pain. Hormones and biological immune agents may also be effective in some cases. Competing Interests: Declaration of competing interest None. (Copyright © 2022. Published by Elsevier B.V.)