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Cellular and molecular basis of therapeutic approaches to breast cancer.

Authors :
El-Tanani M
Al Khatib AO
Al-Najjar BO
Shakya AK
El-Tanani Y
Lee YF
Serrano-Aroca Á
Mishra V
Mishra Y
Aljabali AA
Goyal R
Negi P
Farani MR
Binabaj MM
Gholami A
Binabaj MM
Charbe NB
Tambuwala MM
Source :
Cellular signalling [Cell Signal] 2023 Jan; Vol. 101, pp. 110492. Date of Electronic Publication: 2022 Oct 12.
Publication Year :
2023

Abstract

In recent decades, there has been a significant amount of research into breast cancer, with some important breakthroughs in the treatment of both primary and metastatic breast cancers. It's a well-known fact that treating breast cancer is still a challenging endeavour even though physicians have a fantastic toolset of the latest treatment options at their disposal. Due to limitations of current clinical treatment options, traditional chemotherapeutic drugs, and surgical options are still required to address this condition. In recent years, there have been several developments resulting in a wide range of treatment options. This review article discusses the cellular and molecular foundation of chemotherapeutic drugs, endocrine system-based treatments, biological therapies, gene therapy, and innovative techniques for treating breast cancer.<br /> (Copyright © 2022. Published by Elsevier Inc.)

Details

Language :
English
ISSN :
1873-3913
Volume :
101
Database :
MEDLINE
Journal :
Cellular signalling
Publication Type :
Academic Journal
Accession number :
36241056
Full Text :
https://doi.org/10.1016/j.cellsig.2022.110492