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Macrocyclic Triazolopeptoids: A Promising Class of Extended Cyclic Peptoids.
- Source :
-
Organic letters [Org Lett] 2022 Oct 28; Vol. 24 (42), pp. 7752-7756. Date of Electronic Publication: 2022 Oct 12. - Publication Year :
- 2022
-
Abstract
- Head-to-tail cyclization of linear oligoamides containing 4-benzylaminomethyl-1 H -1,2,3-triazol-1-yl acetic acid monomers afforded a novel class of "extended macrocyclic peptoids". The identification of the conformation in solution for a cyclodimer and the X-ray crystal structure of a cyclic tetraamide are reported.
- Subjects :
- Models, Molecular
Molecular Conformation
Cyclization
Peptoids chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1523-7052
- Volume :
- 24
- Issue :
- 42
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 36223077
- Full Text :
- https://doi.org/10.1021/acs.orglett.2c03062