Reaction of the Hippocampal Microglia to Hyperbaric Oxygen.

Authors :: Kirik OV
Alekseeva OS
Tsyba DL
Korzhevskii DE
Source :: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2022 Sep; Vol. 173 (5), pp. 655-659. Date of Electronic Publication: 2022 Oct 10.
Publication Year :: 2022
Abstract: We studied the reaction of rat hippocampal microgliocytes to hyperbaric oxygen at a pressure of 5 ata (absolute atmosphere). Immunohistochemical analysis with selective macrophage marker CD68 (ED1) and microglial marker Iba-1 allowed separate analysis of these two cell populations. It was shown that macrophages do not significantly contribute to reactive changes in the total pool of Iba-1 <superscript>+</superscript> hippocampal cells induced by hyperbaric oxygen.<br /> (© 2022. Springer Science+Business Media, LLC, part of Springer Nature.)