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[The role of gut microbiota dysbiosis in the occurrence and development of inflammatory bowel disease and its prevention and control strategies].

Authors :
Yang ZY
Li M
Source :
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] [Zhonghua Yu Fang Yi Xue Za Zhi] 2022 Sep 06; Vol. 56 (9), pp. 1175-1181.
Publication Year :
2022

Abstract

The occurrence of inflammatory bowel disease (IBD) is related to environmental factors, host immune status, genetic susceptibility and flora imbalance. With the development of sequencing technologies, the relationship between intestinal microbiota and IBD has been further studied and confirmed in many aspects. This article summarizes the characteristics of microbiota alterations in patients with IBD, as well as the role and mechanisms of microbiota dysbiosis in the onset and development of IBD, and discusses the research status of therapies based on intestinal microbiota, prospecting the future of intestinal flora in the prevention, diagnosis, treatment and prognosis of IBD.

Details

Language :
Chinese
ISSN :
0253-9624
Volume :
56
Issue :
9
Database :
MEDLINE
Journal :
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]
Publication Type :
Academic Journal
Accession number :
36207877
Full Text :
https://doi.org/10.3760/cma.j.cn112150-20211008-00936