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[Hepatotropic action of benzobamil in CCl4 poisoning].

Authors :
VengerovskiÄ­ AI
Sedykh IM
Saratikov AS
Source :
Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1987 Aug; Vol. 104 (8), pp. 192-5.
Publication Year :
1987

Abstract

The administration of an antiepileptic drug--benzobamilum-to rats with CCl4-induced hepatitis prevents the development of liver parenchyma necrosis, promotes the retention of normal enzyme activity in hepatocytes, stimulates the excretory and antitoxic liver functions. The drug has antioxidant properties, inhibits the production of lysophosphatidylcholine and the reduction in phosphatidylcholine content in the liver homogenates but fails to intensify CCl4-induced steatosis.

Details

Language :
Russian
ISSN :
0365-9615
Volume :
104
Issue :
8
Database :
MEDLINE
Journal :
Biulleten' eksperimental'noi biologii i meditsiny
Publication Type :
Academic Journal
Accession number :
3620680