Back to Search
Start Over
The 2022 Update of IUIS Phenotypical Classification for Human Inborn Errors of Immunity.
- Source :
-
Journal of clinical immunology [J Clin Immunol] 2022 Oct; Vol. 42 (7), pp. 1508-1520. Date of Electronic Publication: 2022 Oct 06. - Publication Year :
- 2022
-
Abstract
- The International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) reports here the 2022 updated phenotypic classification, which accompanies and complements the most-recent genotypic classification. This phenotypic classification is aimed for clinicians at the bedside and focuses on clinical features and laboratory phenotypes of specific IEI. In this classification, 485 IEI underlying phenotypes as diverse as infection, malignancy, allergy, auto-immunity and auto-inflammation are described, including 55 novel monogenic defects and 1 autoimmune phenocopy. Therefore, all 485 diseases of the genetic classification are presented in this paper in the form of colored tables with essential clinical or immunological phenotype entries.<br /> (© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Details
- Language :
- English
- ISSN :
- 1573-2592
- Volume :
- 42
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Journal of clinical immunology
- Publication Type :
- Academic Journal
- Accession number :
- 36198931
- Full Text :
- https://doi.org/10.1007/s10875-022-01352-z