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Right ventricular size and function evaluated by various echocardiographic indices in dogs with pulmonary hypertension.
- Source :
-
Journal of veterinary internal medicine [J Vet Intern Med] 2022 Nov; Vol. 36 (6), pp. 1882-1891. Date of Electronic Publication: 2022 Sep 28. - Publication Year :
- 2022
-
Abstract
- Background: Three-dimensional (3D) echocardiography and 2-dimensional (2D) strain measurements of the right ventricle (RV) are important indices in humans with pulmonary hypertension (PH) and need further evaluation in dogs with PH.<br />Objectives: To evaluate various RV size and function indices in dogs with PH and to examine differences between pre- and postcapillary PH.<br />Animals: A total of 311 client-owned dogs: 100 dogs with PH, 31 with postcapillary and 69 with precapillary PH, and 211 healthy control dogs.<br />Methods: Retro- and prospective, multicenter study. Size and function of the RV was determined using several indices, derived using dedicated RV software, including 3D RV end-diastolic volume (EDVn), end-systolic volume (ESVn), ejection fraction, 2D global and free wall RV longitudinal strain (RVLS), end-diastolic area, end-systolic area, fractional area change, tricuspid annular plane systolic excursion, and tissue Doppler imaging-derived systolic myocardial velocity of the lateral tricuspid annulus (S'n).<br />Results: The EDVn (1.8 vs 2.5 mL/kg <superscript>0.942</superscript> , P < .01) and ESVn (0.8 vs 1.2 mL/kg <superscript>0.962</superscript> , P < .001) were significantly larger in the PH group compared to healthy controls. Free wall RVLS was decreased in dogs with severe PH compared to controls (-24% vs -29.6%, P < .001). Dogs with precapillary PH had worse RV systolic function than dogs with postcapillary PH.<br />Conclusion: Three-dimensional echocardiography of the RV is a promising tool to detect RV changes in dogs with PH. Also, 2D strain measurements are able to detect decreased RV function and offer several advantages compared to conventional indices.<br /> (© 2022 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine.)
- Subjects :
- Animals
Dogs
Echocardiography veterinary
Echocardiography methods
Heart Ventricles anatomy & histology
Heart Ventricles diagnostic imaging
Prospective Studies
Dog Diseases diagnostic imaging
Hypertension, Pulmonary diagnostic imaging
Hypertension, Pulmonary veterinary
Ventricular Function, Right
Subjects
Details
- Language :
- English
- ISSN :
- 1939-1676
- Volume :
- 36
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Journal of veterinary internal medicine
- Publication Type :
- Academic Journal
- Accession number :
- 36168939
- Full Text :
- https://doi.org/10.1111/jvim.16496