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Pro-Con Debate: The Clinical (Ir)relevance of the Lower Limit of Cerebral Autoregulation for Anesthesiologists.
- Source :
-
Anesthesia and analgesia [Anesth Analg] 2022 Oct 01; Vol. 135 (4), pp. 734-743. Date of Electronic Publication: 2022 Sep 15. - Publication Year :
- 2022
-
Abstract
- In this Pro-Con commentary article, we discuss whether the lower limit of cerebral autoregulation is clinically relevant for anesthesiologists. The central question regarding this issue is whether mean arterial blood pressure below the lower limit of autoregulation is detrimental for the brain. The Pro side argues that continuous monitoring of cerebral autoregulation has revealed an association between going below the lower limit and mortality in the critically ill patient. Conversely, the Con side argues that cerebral autoregulation is only one of various defense mechanisms of the brain that protect against cerebral hypoperfusion, and that cerebral autoregulation may be more important to protect against intracranial hypertension.<br />Competing Interests: Conflicts of Interest: See Disclosures at the end of the article.<br /> (Copyright © 2022 International Anesthesia Research Society.)
Details
- Language :
- English
- ISSN :
- 1526-7598
- Volume :
- 135
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Anesthesia and analgesia
- Publication Type :
- Academic Journal
- Accession number :
- 36108190
- Full Text :
- https://doi.org/10.1213/ANE.0000000000006123