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Ocular Toxoplasmosis.

Authors :
Goh EJH
Putera I
La Distia Nora R
Mahendradas P
Biswas J
Chee SP
Testi I
Pavesio CE
Curi ALL
Vasconcelos-Santos DV
Arora A
Gupta V
de-la-Torre A
Agrawal R
Source :
Ocular immunology and inflammation [Ocul Immunol Inflamm] 2023 Sep; Vol. 31 (7), pp. 1342-1361. Date of Electronic Publication: 2022 Sep 12.
Publication Year :
2023

Abstract

Introduction: Ocular toxoplasmosis is the leading cause of posterior uveitis worldwide, affecting individuals acrossdifferent age groups. The key to reducing vision loss includes prompt diagnosis and treatment. However, despite the prevalence of ocular toxoplasmosis, there has been little consensus regarding its pathophysiology,clinical features, diagnosis, and especially management.<br />Methods: The data sources were literature reviews, including Pub Med and Medline databases. Search terms included toxoplasmosis, retinitis, vasculitis, vitritis, uveitis alone or in combination with, serum, aqueous, vitreous eye, ocular and review.<br />Results: In this review paper, we have sought to provide an overview of the pathophysiology, epidemiology, and clinical features of the disease, both based on current literature and our own clinical experience. We have also discussed the use of serology, ocular fluid, and ophthalmic investigations that could further facilitate the diagnosis of ocular toxoplasmosis.Different management strategies have been reported worldwide, including newer approaches such as local therapy.<br />Conclusion: A better understanding of critical aspects of ocular toxoplasmosis will hopefully lead to reduced morbidity, including blindness associated with this condition.

Details

Language :
English
ISSN :
1744-5078
Volume :
31
Issue :
7
Database :
MEDLINE
Journal :
Ocular immunology and inflammation
Publication Type :
Academic Journal
Accession number :
36095008
Full Text :
https://doi.org/10.1080/09273948.2022.2117705