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Liver cirrhosis in children - the role of imaging in the diagnostic pathway.

Authors :
Herrmann J
Petit P
Grabhorn E
Lenz A
Jürgens J
Franchi-Albella S
Source :
Pediatric radiology [Pediatr Radiol] 2023 Apr; Vol. 53 (4), pp. 714-726. Date of Electronic Publication: 2022 Aug 30.
Publication Year :
2023

Abstract

Liver cirrhosis in children is a rare disease with multifactorial causes that are distinct from those in adults. Underlying reasons include cholestatic, viral, autoimmune, hereditary, metabolic and cardiac disorders. Early detection of fibrosis is important as clinical stabilization or even reversal of fibrosis can be achieved in some disorders with adequate treatment. This article focuses on the longitudinal evaluation of children with chronic liver disease with noninvasive imaging tools, which play an important role in detecting cirrhosis, defining underlying causes, grading fibrosis and monitoring patients during follow-up. Ultrasound is the primary imaging modality and it is used in a multiparametric fashion. Magnetic resonance imaging and computed tomography are usually applied second line for refined tissue characterization, clarification of nodular lesions and full delineation of abdominal vessels, including portosystemic communications.<br /> (© 2022. The Author(s).)

Details

Language :
English
ISSN :
1432-1998
Volume :
53
Issue :
4
Database :
MEDLINE
Journal :
Pediatric radiology
Publication Type :
Academic Journal
Accession number :
36040526
Full Text :
https://doi.org/10.1007/s00247-022-05480-x