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ARDS in the time of corona: context and perspective.
- Source :
-
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2022 Oct 01; Vol. 323 (4), pp. L431-L437. Date of Electronic Publication: 2022 Aug 23. - Publication Year :
- 2022
-
Abstract
- For more than 2 years, COVID-19 has been holding the world at awe with new waves of infections, novel mutants, and still limited (albeit improved) means to combat SARS-CoV-2-induced respiratory failure, the most common and fatal presentation of severe COVID-19. In the present perspective, we draw from the successes and-mostly-failures in previous acute respiratory distress syndrome (ARDS) work and the experiences from COVID-19 to define conceptual barriers that have so far hindered therapeutic breakthroughs in this deadly disease, and to open up new avenues of thinking and thus, ultimately of therapy.
- Subjects :
- Humans
SARS-CoV-2
COVID-19
Respiratory Distress Syndrome
Subjects
Details
- Language :
- English
- ISSN :
- 1522-1504
- Volume :
- 323
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- American journal of physiology. Lung cellular and molecular physiology
- Publication Type :
- Report
- Accession number :
- 35997290
- Full Text :
- https://doi.org/10.1152/ajplung.00432.2021