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Evolution of zygomycete secretomes and the origins of terrestrial fungal ecologies.

Authors :
Chang Y
Wang Y
Mondo S
Ahrendt S
Andreopoulos W
Barry K
Beard J
Benny GL
Blankenship S
Bonito G
Cuomo C
Desiro A
Gervers KA
Hundley H
Kuo A
LaButti K
Lang BF
Lipzen A
O'Donnell K
Pangilinan J
Reynolds N
Sandor L
Smith ME
Tsang A
Grigoriev IV
Stajich JE
Spatafora JW
Source :
IScience [iScience] 2022 Aug 02; Vol. 25 (8), pp. 104840. Date of Electronic Publication: 2022 Aug 02 (Print Publication: 2022).
Publication Year :
2022

Abstract

Fungi survive in diverse ecological niches by secreting proteins and other molecules into the environment to acquire food and interact with various biotic and abiotic stressors. Fungal secretome content is, therefore, believed to be tightly linked to fungal ecologies. We sampled 132 genomes from the early-diverging terrestrial fungal lineage zygomycetes (Mucoromycota and Zoopagomycota) and characterized their secretome composition. Our analyses revealed that phylogeny played an important role in shaping the secretome composition of zygomycete fungi with trophic mode contributing a smaller amount. Reconstruction of the evolution of secreted digestive enzymes revealed lineage-specific expansions, indicating that Mucoromycota and Zoopagomycota followed different trajectories early in their evolutionary history. We identified the presence of multiple pathogenicity-related proteins in the lineages known as saprotrophs, suggesting that either the ecologies of these fungi are incompletely known, and/or that these pathogenicity-related proteins have important functions associated with saprotrophic ecologies, both of which invite further investigation.<br />Competing Interests: The authors declare no conflict of interest.<br /> (© 2022 The Author(s).)

Details

Language :
English
ISSN :
2589-0042
Volume :
25
Issue :
8
Database :
MEDLINE
Journal :
IScience
Publication Type :
Academic Journal
Accession number :
35996588
Full Text :
https://doi.org/10.1016/j.isci.2022.104840