Coats disease in female population: A comparison of clinical presentation and outcomes.

Purpose: To compare clinical characteristics at presentation and outcomes of Coats disease between females and males.
Methods: In this retrospective, consecutive case series we included all children diagnosed with Coats disease in a single tertiary referral center. Initial clinical presentation, treatment and outcomes were collected.
Results: A total of 158 children were included, of whom 29 (18.3%) were females and 11 (6.9%) had bilateral involvement. Age at diagnosis and disease stage were similar between females and males. Females had more bilateral involvement ( p < 0.001) and tended to have a worse visual acuity at diagnosis ( p = 0.05). At last follow-up, visual acuity and anatomical outcome after treatment were similar between genders.
Conclusion: Female patients with Coats disease had more bilateral involvement and tended to have worse visual acuity at presentation. Clinical presentation and outcomes seemed to be similar between genders.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2022 Piquin, Chapron, Abdelmassih, Martin, Edelson, Caputo and Metge.)