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Antimicrobial resistance among clinical Vibrio cholerae non-O1/non-O139 isolates: systematic review and meta-analysis.
- Source :
-
Pathogens and global health [Pathog Glob Health] 2023 May; Vol. 117 (3), pp. 235-244. Date of Electronic Publication: 2022 Aug 19. - Publication Year :
- 2023
-
Abstract
- Non-O1/non-O139 Vibrio cholerae (NOVC) are nonpathogenic or asymptomatic colonizers in humans, but they may be related to intestinal or extra-intestinal (severe wound infections or sepsis) infections in immunocompromised patients.The present study aimed to evaluate the weighted pooled resistance (WPR) rates in clinical NOVC isolates based on different years, areas, quality, antimicrobial susceptibility testing (AST), and resistance rates. We systematically searched the articles in PubMed, Scopus, and Embase (until January 2020). Data analyses were performed using the Stata software program (version 17). A total of 16 studies that had investigated 824 clinical NOVC isolates were included in the meta-analysis. The majority of the studies were conducted in Asia (n = 14) and followed by Africa (n = 2). The WPR rates were as follows: erythromycin 10%, ciprofloxacin 5%, cotrimoxazole 27%, and tetracycline 13%. There was an increase in resistance to ciprofloxacin, nalidixic acid, and gentamicin, norfloxacin during the period from 2000 to 2020. On the contrary, there was a decreased resistance to erythromycin, tetracycline, chloramphenicol, cotrimoxazole, ampicillin, streptomycin, kanamycin, and neomycin during the period from 2000 to 2020. The lowest resistance rate were related to gentamicin, kanamycin, ciprofloxacin, and chloramphenicol against NOVC strains. However, temporal changes in antimicrobial resistance rate were found in our study. We established continuous surveillance, careful appropriate AST, and limitations on improper antibiotic usage, which are essential, especially in low-income countries.
- Subjects :
- Humans
Anti-Bacterial Agents pharmacology
Anti-Bacterial Agents therapeutic use
Trimethoprim, Sulfamethoxazole Drug Combination
Drug Resistance, Bacterial
Ciprofloxacin
Tetracycline
Chloramphenicol
Kanamycin
Erythromycin
Gentamicins
Microbial Sensitivity Tests
Vibrio cholerae non-O1
Cholera drug therapy
Cholera epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 2047-7732
- Volume :
- 117
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Pathogens and global health
- Publication Type :
- Academic Journal
- Accession number :
- 35983997
- Full Text :
- https://doi.org/10.1080/20477724.2022.2114620