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Transfusion Strategies for Hemostatic Blood Products in Critically Ill Children: A Narrative Review and Update on Expert Consensus Guidelines.

Authors :
Valentine SL
Cholette JM
Goobie SM
Source :
Anesthesia and analgesia [Anesth Analg] 2022 Sep 01; Vol. 135 (3), pp. 545-557. Date of Electronic Publication: 2022 Aug 17.
Publication Year :
2022

Abstract

Critically ill children commonly receive coagulant products (plasma and/or platelet transfusions) to prevent or treat hemorrhage or correct coagulopathy. Unique aspects of pediatric developmental physiology, and the complex pathophysiology of critical illness must be considered and balanced against known transfusion risks. Transfusion practices vary greatly within and across institutions, and high-quality evidence is needed to support transfusion decision-making. We present recent recommendations and expert consensus statements to direct clinicians in the decision to transfuse or not to transfuse hemostatic blood products, including plasma, platelets, cryoprecipitate, and recombinant products to critically ill children.<br />Competing Interests: The authors declare no conflicts of interest.<br /> (Copyright © 2022 International Anesthesia Research Society.)

Details

Language :
English
ISSN :
1526-7598
Volume :
135
Issue :
3
Database :
MEDLINE
Journal :
Anesthesia and analgesia
Publication Type :
Academic Journal
Accession number :
35977364
Full Text :
https://doi.org/10.1213/ANE.0000000000006149