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Effects of traditional and novel proteolytic agents on tissue dissolution and dentine microhardness.
- Source :
-
Australian endodontic journal : the journal of the Australian Society of Endodontology Inc [Aust Endod J] 2023 Aug; Vol. 49 (2), pp. 287-294. Date of Electronic Publication: 2022 Aug 11. - Publication Year :
- 2023
-
Abstract
- The study aimed to evaluate the tissue-dissolving ability of papain and bromelain with respect to that of sodium hypochlorite (NaOCl) at the temperatures of 25°C and 60°C. The study also assessed the effects of these proteolytic agents on radicular dentine microhardness. Warming NaOCl, papain and bromelain solutions resulted in significant tissue dissolution at all time intervals (p < 0.001). At 60°C, bromelain showed significantly higher tissue weight loss at every time interval when compared to NaOCl (p < 0.001). All of the three organic tissue dissolvents reduced the microhardness at 1 hr when compared to their respective baseline values. The reduction in microhardness from the baseline reading was statistically significant only in the papain group at 30 min (p = 0.018) and at 60 min (p = 0.03) when compared to the control group. Hence it was concluded that bromelain exerted superior tissue dissolution action, especially when warmed, with minimal effect on dentine microhardness.<br /> (© 2022 Australian Society of Endodontology Inc.)
Details
- Language :
- English
- ISSN :
- 1747-4477
- Volume :
- 49
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Australian endodontic journal : the journal of the Australian Society of Endodontology Inc
- Publication Type :
- Academic Journal
- Accession number :
- 35950879
- Full Text :
- https://doi.org/10.1111/aej.12674