Pharmacokinetic parameters of 1-beta-D-arabinofuranosylcytosine (ara-C) and their relationship to intracellular metabolism of ara-C, toxicity, and response of patients with acute nonlymphocytic leukemia treated with conventional and high-dose ara-C.

Subjects

Subjects :

Acute Disease
Animals
Arabinofuranosylcytosine Triphosphate metabolism
Arabinofuranosyluracil metabolism
Cytarabine therapeutic use
Cytarabine toxicity
Drug Administration Schedule
Humans
Leukemia L1210 metabolism
Metabolic Clearance Rate
Mice
Uridine Kinase metabolism
Cytarabine metabolism
Leukemia drug therapy

Details

Language :

English

ISSN :

0093-7754

Volume :

14

Issue :

2 Suppl 1

Database :

MEDLINE

Journal :

Seminars in oncology

Publication Type :

Academic Journal

Accession number :

3589689