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Case report of transient corneal edema after immunization with adenovirus-vectored COVID-19 vaccine.
- Source :
-
Medicine [Medicine (Baltimore)] 2022 Jul 22; Vol. 101 (29), pp. e30041. Date of Electronic Publication: 2022 Jul 22. - Publication Year :
- 2022
-
Abstract
- Rationale: To report a case of bilateral transient corneal edema presumably associated with adenovirus-vectored coronavirus disease 2019 (COVID-19) vaccination that resolved with eye drops treatment.<br />Patient Concerns: A 55-year-old Asian woman presented with sudden onset of bilateral visual disturbance developed 6 days after immunization with an adenovirus-vectored COVID-19 vaccine (AstraZeneca, London, United Kingdom). She underwent uneventful cataract surgery in right and left eyes 2 months ago and maintained good visual acuity bilaterally. Slit-lamp examination showed bilateral mild corneal edema that was confirmed with anterior segment optical coherent tomography. Anterior chamber and vitreous were clear bilaterally. Both fundi were normal.<br />Diagnoses: The patient was diagnosed with corneal edema following adenovirus-vectored COVID-19 vaccination.<br />Interventions: She was prescribed with prednisolone acetate 1% eye drops bilaterally.<br />Outcomes: Treatment with topical steroid for 2 weeks resulted in resolution of the corneal edema and improvement of the visual acuity bilaterally.<br />Lessons: This case suggests that transient corneal edema can develop following adenovirus-vectored COVID-19 vaccination. Prompt ophthalmologic evaluation and treatment may improve the corneal edema.<br />Competing Interests: The authors have no funding and conflicts of interest to disclose.<br /> (Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.)
Details
- Language :
- English
- ISSN :
- 1536-5964
- Volume :
- 101
- Issue :
- 29
- Database :
- MEDLINE
- Journal :
- Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 35866821
- Full Text :
- https://doi.org/10.1097/MD.0000000000030041