The reliability and validity test of subjective cognitive decline questionnaire 21 with population in a Chinese community.

Background: Subjective cognitive decline-questionnaire 9 (SCD-Q9) was developed to detect SCD complaints at risk of mild cognitive impairment (MCI). However, our previous findings indicated that its coverage might be insufficient. To test this hypothesis, we recently translated SCD-Q21.
Objective: To examine the reliability and validity of this translated SCD-Q21 and to explore its effectiveness for discriminating MCI from controls.
Methods: Item analysis was performed to understand its item discrimination and homogeneity. The Cronbach's α and Spearman-Brown's split-half coefficients were calculated to test its reliability. The Kaiser-Meyer-Olkin (KMO) value, Bartlett's sphericity test, and exploratory factor analysis (EFA) were used to examine its construct validity. The content validity was evaluated using five-grade Likert scale. Finally, the SCD-Q21 scores in MCI and controls were compared.
Results: The difference of each item between the extreme groups was significant. The Cronbach's α coefficient was .913 and Spearman-Brown's split-half coefficient was .894. When performing holding one-out approach, the Cronbach's α coefficient ranged from .906 to .914. The KMO value was .929 and the difference of Bartlett's Sphericity test was significant. All experts scored 5 points when assessing its content. Finally, a significant difference of score was found between MCI and NC groups.
Conclusions: The reliability and validity of the SCD-Q21 are good, which may pave a way for its application in a wider Chinese-speaking population.
(© 2022 The Authors. Brain and Behavior published by Wiley Periodicals LLC.)