A next generation BCG vaccine moves forward.

Competing Interests: HMD was previously funded by the TBVAC2020 Consortium, which was funded by the EU Horizon 2020 programme, the Bill & Melinda Gates funded GC6–74 and GC6–2013 consortia, the EU FP7 funded Concurrent Tuberculosis and Diabetes Mellitus Consortium consortium, and the European and Developing Countries Clinical Trials Partnership funded AE-TBC and ScreenTB consortia, and is a current member of the EDCTP funded TriageTB consortium, which include several of the authors of the VPM1002 study but has had no role in the development of this vaccine.