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Longitudinal electrocardiographic assessment in Brugada syndrome.
- Source :
-
Heart rhythm O2 [Heart Rhythm O2] 2022 Feb 08; Vol. 3 (3), pp. 233-240. Date of Electronic Publication: 2022 Feb 08 (Print Publication: 2022). - Publication Year :
- 2022
-
Abstract
- Background: The type 1 electrocardiographic (ECG) pattern diagnostic of Brugada syndrome (BrS) can be dynamic. Limited studies have rigorously evaluated the temporal stability of the Brugada ECG pattern.<br />Objective: We sought to evaluate fluctuations of the Brugada pattern in serial resting ECGs from BrS patients managed within a large health care system.<br />Methods: In our cohort of BrS patients with at least 2 standard, resting ECGs recorded on separate clinical encounters, we evaluated serial changes in the Brugada pattern and categorized patients into 1 of 3 groups: dynamic was defined as the presence of both type 1 and non-type 1 patterns in available ECGs; the provoked-only group was defined as having a non-type 1 Brugada pattern across resting ECGs; and the persistent group was defined as having a type 1 pattern on all ECGs. We also evaluated the clinical risk in this cohort according to the Shanghai risk score.<br />Results: In 72 patients with BrS (mean age 46 ± 15 years, 69% male), 828 standard, resting ECGs were recorded over a median duration of 30.2 (interquartile range 6.3-68.1) months. The dynamic group comprised 50 (69% of the cohort) patients, the provoked-only group consisted of 17 patients (24% of the cohort), and the persistent group included 5 patients. No significant differences were detected in the total number of ECGs evaluated during the follow-up period between any of the groups. Only sinus node dysfunction and a prior cardiac arrest were associated with the persistent type 1 group. The majority of patients had a low annualized risk of lethal arrhythmic events.<br />Conclusion: Most BrS patients have a dynamic Brugada pattern noted on longitudinal, resting ECGs. Expert consensus statements should provide clarity on the frequency of obtaining resting ECGs in patients suspected of having BrS during follow-up.<br /> (© 2022 Heart Rhythm Society. Published by Elsevier Inc.)
Details
- Language :
- English
- ISSN :
- 2666-5018
- Volume :
- 3
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Heart rhythm O2
- Publication Type :
- Academic Journal
- Accession number :
- 35734292
- Full Text :
- https://doi.org/10.1016/j.hroo.2022.01.011