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Lymphoepithelioma-like carcinoma of the eyelid and ocular adnexa.

Authors :
Shoji MK
Sengillo JD
Abou Khzam R
Dubovy SR
Rong AJ
Source :
Orbit (Amsterdam, Netherlands) [Orbit] 2024 Feb; Vol. 43 (1), pp. 140-146. Date of Electronic Publication: 2022 Jun 22.
Publication Year :
2024

Abstract

A 93-year-old Caucasian woman presented to clinic for evaluation of a progressively enlarging left eyelid mass. Exam revealed a large, indurated, poorly mobile mass involving the left upper eyelid. Imaging demonstrated a crescentic enhancing soft-tissue mass in the left upper eyelid without evidence of deeper orbital involvement. Biopsy demonstrated tumor nests positive for cytokeratin AE1/AE3, P63, and P40 consistent with a diagnosis of eyelid lymphoepithelioma-like carcinoma (LELC). The patient underwent surgical resection with subsequent left upper eyelid reconstruction and adjuvant radiation. She had no clinical evidence of disease recurrence at follow-up. LELC is an uncommon tumor that rarely involves the eyelid and ocular adnexa. Early identification is important due to its malignant potential, as the majority of previously reported cases demonstrated local or distant metastatic spread. Future studies are needed to determine the optimum treatment regimen for this rare periorbital neoplasm.

Details

Language :
English
ISSN :
1744-5108
Volume :
43
Issue :
1
Database :
MEDLINE
Journal :
Orbit (Amsterdam, Netherlands)
Publication Type :
Academic Journal
Accession number :
35733412
Full Text :
https://doi.org/10.1080/01676830.2022.2085305