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Sodium alginate based drug delivery in management of breast cancer.

Authors :
Shaikh MAJ
Alharbi KS
Almalki WH
Imam SS
Albratty M
Meraya AM
Alzarea SI
Kazmi I
Al-Abbasi FA
Afzal O
Altamimi ASA
Singh Y
Singh SK
Dua K
Gupta G
Source :
Carbohydrate polymers [Carbohydr Polym] 2022 Sep 15; Vol. 292, pp. 119689. Date of Electronic Publication: 2022 Jun 02.
Publication Year :
2022

Abstract

Among women, breast cancer (B·C.) is a common form of cancer that can strike either developed or developing countries. In addition to pregnancy-related variables, hormone therapy lifestyle factors (e.g., physical inactivity, smoking, and alcohol use) may all influence the progression of B·C. The creation of anti-B·C. medication carriers with better stability, controlled and targeted administration, and the goal of minimizing unwanted effects has taken a lot of time and effort. Naturally generated biopolymers-based pharmaceutical delivery techniques have attracted attention for their potential use in treating B·C. It's been shown that natural polymers can deliver high medication concentrations to the desired place and provide prolonged release of pharmaceuticals useful in treating B.C. Alginate is one of the most commonly used drug carriers for delayed and targeted release. In present review will discuss the utilization of sodium alginate as an carrier of anticancer drug, such as paclitaxel, doxorubicin, tamoxifen, curcumin, and others.<br /> (Copyright © 2022 Elsevier Ltd. All rights reserved.)

Details

Language :
English
ISSN :
1879-1344
Volume :
292
Database :
MEDLINE
Journal :
Carbohydrate polymers
Publication Type :
Academic Journal
Accession number :
35725179
Full Text :
https://doi.org/10.1016/j.carbpol.2022.119689