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Gestational Trophoblastic Disease: Contemporary Diagnostic Approach.

Authors :
Buza N
Source :
Surgical pathology clinics [Surg Pathol Clin] 2022 Jun; Vol. 15 (2), pp. 197-218. Date of Electronic Publication: 2022 May 20.
Publication Year :
2022

Abstract

Pathologic diagnosis of gestational trophoblastic disease (GTD)-hydatidiform moles and gestational trophoblastic neoplasms-underwent a major shift in the past decade from morphology-based recognition to precise molecular genetic classification of entities, which also allows for prognostic stratification of molar gestations. This article highlights these recent advances and their integration into the routine pathology practice. The traditional gross and histomorphologic features of each entity are also reviewed with special focus on differential diagnoses and their clinical implications.<br />Competing Interests: Disclosure The author has nothing to disclose.<br /> (Copyright © 2022 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1875-9157
Volume :
15
Issue :
2
Database :
MEDLINE
Journal :
Surgical pathology clinics
Publication Type :
Academic Journal
Accession number :
35715158
Full Text :
https://doi.org/10.1016/j.path.2022.02.002