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Monitoring occurrence of SARS-CoV-2 in school populations: A wastewater-based approach.

Authors :
Castro-Gutierrez V
Hassard F
Vu M
Leitao R
Burczynska B
Wildeboer D
Stanton I
Rahimzadeh S
Baio G
Garelick H
Hofman J
Kasprzyk-Hordern B
Kwiatkowska R
Majeed A
Priest S
Grimsley J
Lundy L
Singer AC
Di Cesare M
Source :
PloS one [PLoS One] 2022 Jun 17; Vol. 17 (6), pp. e0270168. Date of Electronic Publication: 2022 Jun 17 (Print Publication: 2022).
Publication Year :
2022

Abstract

Clinical testing of children in schools is challenging, with economic implications limiting its frequent use as a monitoring tool of the risks assumed by children and staff during the COVID-19 pandemic. Here, a wastewater-based epidemiology approach has been used to monitor 16 schools (10 primary, 5 secondary and 1 post-16 and further education) in England. A total of 296 samples over 9 weeks have been analysed for N1 and E genes using qPCR methods. Of the samples returned, 47.3% were positive for one or both genes with a detection frequency in line with the respective local community. WBE offers a low cost, non-invasive approach for supplementing clinical testing and can provide longitudinal insights that are impractical with traditional clinical testing.<br />Competing Interests: The authors have declared that no competing interests exist.

Details

Language :
English
ISSN :
1932-6203
Volume :
17
Issue :
6
Database :
MEDLINE
Journal :
PloS one
Publication Type :
Academic Journal
Accession number :
35714109
Full Text :
https://doi.org/10.1371/journal.pone.0270168